Family Nurse Practitioner Exam

What condition is likely in a patient experiencing elevated liver enzymes after taking statins?

1. Rhabdomyolysis

2. Acute drug-induced hepatitis

3. Acute viral hepatitis

4. Major depressive episode

The correct answer is: Acute drug-induced hepatitis

The scenario presented—elevated liver enzymes following the administration of statins—suggests a likelihood of acute drug-induced hepatitis. Statins are commonly prescribed to manage cholesterol levels, but they can, in some cases, lead to liver enzyme elevations. When a patient experiences heightened liver enzymes after starting statin therapy, this can indicate potential liver injury or inflammation. Drug-induced hepatitis may occur due to an adverse reaction to the medication, reflecting a direct toxic effect on liver cells. It's important to monitor liver function tests in patients taking statins, as this can help detect potential hepatotoxicity early. Other conditions mentioned might also be associated with elevated liver enzymes; however, their clinical context and presentations differ significantly. Rhabdomyolysis typically results in elevated creatine kinase levels and not primarily liver enzymes. Acute viral hepatitis is caused by viral infection and would present differently, likely with additional symptoms indicative of a viral process. A major depressive episode does not directly cause elevated liver enzymes and is unrelated to the biochemical changes stemming from the use of statins. Understanding the linked mechanisms of statin use and liver function is crucial in identifying the likely cause of elevated liver enzymes in a patient, reinforcing the significance of vigilant monitoring in patients on these medications.