Family Nurse Practitioner Exam

What is a common risk associated with atypical antipsychotics such as olanzapine?

1. Increased blood pressure

2. Weight gain and type 2 diabetes risk

3. Shortness of breath

4. Severe allergic reactions

The correct answer is: Weight gain and type 2 diabetes risk

Atypical antipsychotics, including olanzapine, are widely used in the treatment of various psychiatric conditions, but they come with a risk profile that necessitates careful monitoring. One of the most significant concerns associated with olanzapine and similar medications is weight gain, which can lead to an increased risk of developing type 2 diabetes. These medications can impact metabolic pathways and promote weight gain due to changes in appetite and metabolism. The risk of significant weight gain with olanzapine is well documented, and it can contribute to further metabolic issues, including dyslipidemia and insulin resistance. For patients already predisposed to weight-related health issues, the prescription of olanzapine requires a thorough assessment of these risks and ongoing monitoring. In comparison, the other options represent risks that may not be as directly associated with olanzapine. While increased blood pressure can occur, it is not as commonly noted as a primary concern with atypical antipsychotics. Shortness of breath may arise from other factors or conditions rather than being a direct effect of this medication class. Similarly, severe allergic reactions, although possible with any medication, are relatively rare with olanzapine compared to the well-established metabolic side effects. Thus