Family Nurse Practitioner Exam

Which medication is typically administered in a case of PID, assuming Gonorrhea is present?

1. Ceftriaxone and doxycycline

2. Azithromycin and metronidazole

3. Amoxicillin and clarithromycin

4. Tetracycline and rifampin

The correct answer is: Ceftriaxone and doxycycline

The appropriate medication for treating Pelvic Inflammatory Disease (PID) when Gonorrhea is present is a combination of ceftriaxone and doxycycline. Ceftriaxone is a broad-spectrum cephalosporin antibiotic that is effective against Neisseria gonorrhoeae, the bacteria responsible for gonorrhea. Doxycycline is a tetracycline antibiotic that provides coverage for a variety of organisms commonly associated with PID, including Chlamydia trachomatis. The choice of this combination reflects the need to cover both potential pathogens in PID cases effectively. This dual therapy not only addresses the immediate infectious process but also helps in reducing the risk of complications such as tubo-ovarian abscesses and infertility. The other medication combinations listed would not provide the necessary coverage for both Gonorrhea and other potential pathogens involved in PID. For instance, azithromycin and metronidazole primarily target specific bacterial infections and do not adequately address the gonococcal infection. Amoxicillin and clarithromycin also lack sufficient coverage for Neisseria gonorrhoeae, while tetracycline and rifampin are not recommended treatments due to their limited efficacy against the organisms commonly involved in PID. Thus, ceftriaxone and